chase the dream not the competition

KnowledgeBin.org
KnowledgeBin Home / Study Material / Chemistry / Organic Chemistry / Nucleophilic-Substitution-9

Over 1000+ articles, updated everyday...for Free SMS Alerts click here , Engineering Q&A forum here

Invite Friends
Search:     Advanced Search
Browse by category:
 

Nucleophilic-Substitution-9

Vist the new KnowledgeBin forum to ask all your questions!

KnowledgBin.org SMS Registration

Click Here to Register Online

Creative Commons License
KnowledgeBin.org is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.5 India License.

It has been observed that quaternary ammonium hydroxides as well as sulphonium salts preferably yield less substituted alkenes.




For the same reason an isobutyl group shows still less tendency to lose a proton if either an n-propyl or an ethyl group is available in the molecule.

Stearic factors also play a big role in Hoffmann eliminations. It is apparent that the groups eliminated in these reactions are bulkier than those lost in the Saytzeff type of eliminations. So that, it has been found that E2 reactions of alkyl halides can be forced to follow Hofmann type of elimination by sufficiently increasing the bulk of the attacking base or by increasing the degree of branching in the substrate. Treatment of following bromoderivative with base, for instance, gives 1-alkene in preference to 2-alkenes mainly due to stearic strain resulting from the interaction of methyl and tert-butyl groups in the latter alkene.


A similar stearic effect seems to operate when the size of the attacking base is increased, for example



This reaction is used for conversion of nonterminal into terminal derivatives for example

SMS Alerts

SocialTwist Tell-a-Friend

Admission Updates

KnowledgeBin Forum Invite Friends

KnowledgeBin Forum Discuss In Forum

KnowledgeBin RSS Subscribe to Updates
Views: 605
Votes: 0

Others In This Category
document Isomersim for IITJEE
document Aldehydes & Ketones
document Carboxylic Acids
document Amines
document Acid derivatives - 1
document Acid Derivatives -2
document Acid - Derivatives-3
document Acid - Derivatives-4
document Acid - Derivatives-5
document Alcohol-Diol-Triol-1
document Alcohol-Diol-Triol-2
document Alcohol-Diol-Triol-3
document Alcohol-Diol-Triol-4
document Alcohol-Diol-Triol-5
document Alcohol-Diol-Triol-6
document Alcohol-Diol-Triol-7
document Alcohol-Diol-Triol-8
document Alcohol-Diol-Triol-9
document Aldehydes - Ketones-1
document Aldehydes - Ketones-2
document Aldehydes-Ketones-3
document Aldehydes-Ketones-4
document Aldehydes-Ketones-5
document Aldehydes-Ketones-6
document Aldehydes-Ketones-7
document Alkadienes-1
document Alkadienes-2
document Alkadienes-3
document Alkadienes-4
document Alkadienes-5
document Alkadienes-6
document Alkadienes-7
document Alkadienes-8
document Alkanes-Paraffins-1
document Alkanes-Paraffins-2
document Alkanes-Paraffins-3
document Alkanes-Paraffins-4
document Alkanes-Paraffins-5
document Alkanes-Paraffins-6
document Alkanes-Paraffins-7
document Alkanes-Paraffins-8
document Alkanes-Paraffins-9
document Alkyl-Halides-1
document Alkyl-Halides-2
document Alkyl-Halides-3
document Alkyl-Halides-4
document Alkyl-Halides-5
document Alkyl-Halides-6
document Alkynes-1
document Alkynes-2
document Alkynes-3
document Alkynes-4
document Alkynes-5
document Alkynes-6
document Amines-Urea-1
document Amines-Urea-2
document Amines-Urea-3
document Amines-Urea-4
document Amines-Urea-5
document Amines-Urea-6
document Amines-Urea-7
document Carboxyllic-Acid-1
document Carboxyllic-Acid-2
document Carboxyllic-Acid-3
document Carboxyllic-Acid-4
document Carboxyllic-Acid-5
document Carboxyllic-Acid-6
document common-names-geneva-system-1
document common-names-geneva-system-2
document common-names-geneva-system-3
document common-names-geneva-system-4
document common-names-geneva-system-5
document common-names-geneva-system-6
document common-names-geneva-system-7
document common-names-geneva-system-8
document common-names-geneva-system-9
document Ethers-Epoxides-1
document Ethers-Epoxides-2
document Ethers-Epoxides-3
document Ethers-Epoxides-4
document Ethers-Epoxides-5
document Ethers-Epoxides-6
document Ethers-Epoxides-7
document Ethers-Epoxides-8
document fundamentals-of-organic-chemistry-1
document fundamentals-of-organic-chemistry-2
document fundamentals-of-organic-chemistry-3
document fundamentals-of-organic-chemistry-4
document fundamentals-of-organic-chemistry-5
document fundamentals-of-organic-chemistry-6
document fundamentals-of-organic-chemistry-7
document fundamentals-of-organic-chemistry-8
document fundamentals-of-organic-chemistry-9
document fundamentals-of-organic-chemistry-10
document fundamentals-of-organic-chemistry-11
document Isomerism-1
document Isomerim-2
document Isomerism-3
document Isomerism-4
document Isomerism-5
document Isomerism-6
document Nucleophilic-Substitution-1
document Nucleophilic-Substitution-2
document Nucleophilic-Substitution-3
document Nucleophilic-Substitution-4
document Nucleophilic-Substitution-5
document Nucleophilic-Substitution-6
document Nucleophilic-Substitution-7
document Nucleophilic-Substitution-8
document organometallic-grignard-reagent-1
document organometallic-grignard-reagent-2
document organometallic-grignard-reagent-3
document organometallic-grignard-reagent-4
document organometallic-grignard-reagent-5
document Stereochemistry-1
document Stereochemistry-2
document Stereochemistry-3
document Stereochemistry-4
document Stereochemistry-5
document Stereochemistry-6
document Stereochemistry-7
document How to study Organic Chemistry
document CYCLOALKANES
document HELPFUL INFORMATION OF SOME OXIDIZING AGENTS IN ORGANIC CHEMISTRY
document How To Study Organic Chemistry
document [TRICK] THE DOUBLE BOND EQUIVALENCE CONCEPT
document How To Learn Organic Chemistry
document Important Sequences of Organic Chemistry
About Us | Contact Us | Feedback | Copyright © 2008 KnowledgeBin.org™ All rights reserved


RSS
Powered by KnowledgeBin (The EveryThing Of IITJEE, AIEEE, BITSAT & All Other Engineering Exams)